Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Acute Eosinophilic Pneumonia
- Radiologic Findings
- Initial chest PA shows diffuse increased interstitial markings and reticular densities in both lungs with bilateral small pleural effusion. Note consolidation in left lower lung zone.
Same-day HRCT shows linear densities by diffuse smooth thickening of interlobular septa, and patchy ground-glass opacities, multiple areas of consolidation in both lungs, and bilateral small pleural effusion.
Initial CBC profile showed no peripheral eosinophilia but was followed by markedly increased eosinophils in peripheral blood one day later.
On second hospital day, bronchoalveolar lavage and transbronchial lung biopsy revealed increased eosinophil counts (~60%) and eosinophilic infiltration in the interstitium and the alveolar space.
On 3rd hospital day, chest radiograph showed marked resolution of pulmonary infiltrates.
His symptoms resolved rapidly without any specific treatment. No corticosteroid was given.
- Brief Review
- To add some points to brief discussion of case No. 105, peripheral eosinophilia may not be presented in the early phase of the disease. Most patients respond rapidly on corticosteroid, but spontaneous resolution was reported in some patients.
- References
- 1. Cheon JE, Lee KS, Jung GS, Chung MH, Cho YD. Acute eosinophilic pneumonia: radiographic and CT findings in six patients. AJR 1996;167:1195-1199
2. King MA, Pope-Harman AL, Allen JN, Christoforidis GA, Christoforidis AJ. Acute eosinophilic pneumonia: radiologic and clinical features. Radiology:1997;203:715-719
- Keywords
- Lung, Eosinophilic lung disease,